الاثنين، 23 مايو 2011

Graduate Program in Sexual Health wins award at WAS 2009

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I have just returned from the World Association for Sexual cheap viagra Congress in Gotenberg Sweden.
The BIG news in that our program was awarded the WAS AWARD FOR EXCELLENCE & INNOVATION IN SEXUALITY EDUCATION 2009.
This is the equivalent of winning an Oscar award for sex education.

Do let me know (P.Weerakoon@usyd.edu.au) if you want to be a part of this award winning group.

الثلاثاء، 3 مايو 2011

2. What is Sildenafil?

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Sildenafil improves acquisition and retention of memory in mice
by
Singh N, Parle M. Pharmacology Division,
Department of Pharmaceutical Sciences,
Guru Jambheshwar University (G.J.U.)
Post Box 38, Hisar 125 001.
Indian J Physiol Pharmacol. 2003 Jul;47(3):318-24.


ABSTRACT

Sildenafil (Viagra) has been introduced recently in market to correct male impotency and has gained immense popularity for its dramatic effects all over the world. The present study was designed to investigate the effect of cialis on learning and memory in mice using elevated plus maze. A total of XV groups of animals were employed in the present study. Central cholinergic pathways play a crucial role in learning and memory processes. Physostigmine, an anticholinesterase agent (0.5 mg, 1.0 mg kg(-1), i.p) was employed for its memory enhancing property and alprazolam a benzodiazepine receptor agonist served as a memory-impairing agent. In the present study, alprazolam produced anterograde amnesia (at 0.5 mg kg(-1), i.p) and retrograde amnesia (at 0.25 mg, 0.5 mg, 0.75 mg kg(-1), i.p.) in separate groups of animals. Caffeine at 5 mg, 10 mg and 20 mg kg(-1), i.p. (an established psychostimulant) did not show any significant change in learning and memory of mice. Sildenafil (at 8 mg kg(-1), i.p.) administered 30 minutes prior to training on first day produced a marginal decrease in transfer latency time on first day; whereas, sildenafil (at 2 mg, 4 mg, 8 mg kg(-1), i.p.) administered immediately after training on first day produced a dose-dependent improvement of memory in mice. However, further studies need to be carried out to elucidate the underlying mechanism of sildenafil as a memory enhancer.

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